Hiding in Plain Sight: Learning the Signs of Narcolepsy
People living with narcolepsy may experience symptoms for more than a decade before receiving a proper diagnosis . That’s what happened to Meaghan – when she went undiagnosed and it felt like narcolepsy started to take over her life and limit her daily functioning.
Cataplexy is the sudden, generally brief, loss of muscle tone with retained consciousness. It is usually triggered by strong emotions, like laughter, surprise or anger. Episodes of cataplexy triggered by laughter may involve only certain muscle groups, such as arms and legs (e.g., knees buckling), the head and neck (e.g., head dropping), or the face and jaw (e.g., sagging of the jaw, slurred speech, eyelid drooping). Complete collapse can also occur as a result of a variety of emotions.
Jazz strives to create a workplace culture that supports a diverse, multicultural workforce and provides an inclusive environment where all employees are empowered to contribute and succeed.
Low Intensity Therapy for first-line, unfit AML (Phase 1b)
CPX-351 + various targeted agents4
First-line, fit AML (Phase 1b)
CPX-3513
Low Intensity Dosing for higher risk MDS
IMGN6321
CD123+ Hematological malignancies
IMGN632 +/- venetoclax/azacitidine1
CD123+ AML (Phase 1b/2)
PHASE 2
JZP-3854
Essential tremor (Phase 2b)
Defibrotide
Prevention of aGvHD
Defibrotide4
Prevention of CAR-T associated neurotoxicity
CPX-351 + venetoclax3
de novo or R/R AML
CPX-3515
HR-MDS (EMSCO)
CPX-3515
R/R AML (COG)
JZP-458 (recombinant Erwinia asparaginase)4
ALL/LBL (pivotal Phase 2/3)
PHASE 3
JZP-258
Cataplexy & EDS in narcolepsy
JZP-258
Idiopathic hypersomnia
Defibrotide
Prevention of VOD
CPX-3515
AML or HR-MDS (AML19 & AML18)
CPX-3515
Newly diagnosed adults with standard- and HR-AML (AMLSG)
CPX-3514,5
Newly diagnosed pediatric patients (COG)
REGULATORY
Solriamfetol EU
EDS in OSA and Narcolepsy
Sleep/Neuroscience
Hematology/Oncology
1Opt-in opportunity
2Partnered collaboration
3Jazz & MD Anderson Cancer Center collaboration study
4Planned
5Cooperative group study
Jazz Pharmaceuticals is a global biopharmaceutical company dedicated to bringing life-changing medicines to people with limited or no options, so they can live their lives more fully.
By unlocking biopharmaceutical discoveries to develop novel medicines, we are giving thousands of people around the world the opportunity to redefine what’s possible.
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