For nearly 20 years, Jazz has been at the forefront of pioneering innovative medicines for rare, hard-to-treat disorders. Jazz has launched Pioneering Pathways to showcase the people, and pioneering research, behind Jazz’s unique scientific approach. Watch the inaugural episode that focuses on idiopathic hypersomnia and features perspectives from across the community.

To address the low understanding of idiopathic hypersomnia (IH), Jazz partnered with the Hypersomnia Foundation to launch I Have IH, a disease awareness campaign aimed at increasing knowledge of IH. In a previous Our Stories article, we focused on results from the patient and supporter surveys that unveiled the difficult and prolonged diagnosis journey people with IH and their supporters often endure. In this piece, we focus on additional results from the surveys that show the debilitating effects IH has on day-to-day life.

Idiopathic hypersomnia (IH) is a debilitating neurologic sleep disorder that is not common or widely understood. To address this lack of knowledge around the condition, Jazz partnered with the Hypersomnia Foundation to launch I Have IH, an awareness campaign highlighting physician, patient and supporter perspectives to better understand the level of knowledge of IH and its real-life impact on those living with the disorder.

When Willow, an active, healthy five-year-old began experiencing unusual symptoms like decreased appetite and fatigue, her mother, Valerie, didn’t assume the worst. But after her bloodwork came back abnormal – showing a critically low platelet count – Valerie’s concerns grew. It was around midnight the following day when a medical team from Children’s National Hospital in DC delivered the news that Willow had acute lymphoblastic leukemia (ALL).

Receiving a diagnosis of any kind has implications not just for the person on the receiving end, but also for their family, friends and the people closest to them. As part of our commitment to patients and their care teams, this National Family Caregivers Month, we shine a light on this essential role and its many nuances.

During National Family Caregivers Month, we recognize and honor family caregivers who dedicate time and resources to caring for their loved ones. Jazz is committed to raising awareness of the essential role that caregivers play and the challenges they face, and to educating communities on ways to increase support for them.

Watch the latest episode in the Pioneering Pathways interactive series to learn more about one mechanism of action that is being investigated to help address the unmet needs of patients living with post-traumatic stress disorder.

Bispecific antibodies are showing potential in the fight against HER2-expressing cancers. This innovative approach is designed to target two specific protein receptors, providing a new and effective way to treat aggressive forms of cancer that overexpress the HER2 protein. With their ability to simultaneously target two different antigens, bispecific antibodies offer a novel approach to treating solid tumors, including the possibility for new first-line treatments.

Given the limited recognition of idiopathic hypersomnia, there is not substantial data on the burden of symptoms on those living with the disorder. Recent real-world evidence from a self-reported survey published in Nature and Science of Sleep reveals more insights around idiopathic hypersomnia symptoms and patients’ satisfaction with treatment regimens.

November is National Epilepsy Awareness Month – a milestone that allows us to pause and reflect on both the progress the community has made for people living with this condition and their continued unmet needs. This time of reflection is especially important for people diagnosed with rare forms of epilepsy, as well as their families and caregivers, who are continuing to search for improved therapeutic outcomes.

Recently, Mat Davis, PhD, vice president and head of data science, presented at the 2023 STAT Summit where he shared a key moment in his career when he learned the necessity of breaking down silos to fully embrace quantitative experts across the three avenues of drug development.

Jazz’s oncology efforts are focused on delivering innovation to improve patient care, quality of life, and advancing scientific understanding of cancers with high unmet needs like acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL), which often affect children. To learn more about progress in the fight against these childhood blood cancers, Jazz’s Abizer Gaslightwala spoke with pediatric hematologist/oncologist Dr. Rachel Rau.